Reproductive hormones regulate the selective permeability of the blood-brain barrier

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IN PRESS OF Reproductive hormones regulate the selective permeability of the blood - brain barrier ☆

Article history: Received 23 October 2007 Received in revised form 21 February 2008 Accepted 25 February 2008 Available online xxxx EC TE D PR Reproductive hormones have been demonstrated tomodulate both gapand tight-junctionprotein expression in reproductive tissues and endometrium,however the effects of changes in reproductive hormoneson the selective permeability of the blood-brain barrier (...

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Reproductive hormones regulate the selective permeability of the blood-brain barrier.

Reproductive hormones have been demonstrated to modulate both gap and tight junction protein expression in the ovary and other reproductive tissues, however the effects of changes in reproductive hormones on the selective permeability of the blood-brain barrier (BBB) remain unclear. Age-related declines in BBB integrity correlate with the loss of serum sex steroids and increase in gonadotropins...

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Author's Personal Copy Reproductive Hormones Regulate the Selective Permeability of the Blood-brain Barrier ☆

In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: a r t i c l e i n f o a b s t r a c t Reproductive hormones have been demonstrated to modulate both gap and tight junction p...

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Quantitative evaluation of Blood Brain Barrier permeability in transient focal cerebral ischemia in the rat

Introduction: Development of brain edema following focal cerebral ischemia exacerbates primary ischemic injury. Blood brain barrier (BBB) opening is an important part of edema named as vasogenic brain edema. In this study, quantitative alterations of BBB permeability is experimentally evaluated using transient focal cerebral ischemia in the rat. Methods: Two groups of male rats (ischemic and sh...

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Introduction: Recent studies have reported that the Aloe vera (Aloe barbadensis miller) plant has anti-inflammatory and antioxidant effects. This study evaluated the neuroprotective effects of different doses of Aloe vera extract after traumatic brain injury (TBI) in male rats. Materials and Methods:  In this study, 70 male rats were divided into 2 groups; each group consists of 5 of sub-g...

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

سال: 2008

ISSN: 0925-4439

DOI: 10.1016/j.bbadis.2008.02.011